topiramate will lower the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/keep track of.
Once acute symptomatology has long been adequately controlled with diazepam injection, the affected person could possibly be placed on oral therapy if additional cure expected
withdrawal reactions, such as seizures, which can be daily life-threatening; use gradual taper when discontinuing therapy to decrease withdrawal reactions hazard
Coadministration of other CNS depressants or Liquor intake may possibly potentiate CNS-depressant results of diazepam
diazepam improves toxicity of oliceridine by Other (see remark). Modify Therapy/check Closely. remark: Anticholinergic medicines may improve possibility of more info urinary retention and/or intense constipation, which can result in paralytic ileus.
Reserve concomitant prescribing of these medications in individuals for whom other treatment alternatives are inadequate. Limit dosages and durations to the least essential. keep an eye on closely for signs of respiratory melancholy and sedation.
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sparsentan will minimize the level or influence of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use warning/keep an eye on. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and cuts down efficacy connected to these substrates.
Limit dosages and durations into the minimal required. Follow people for symptoms and signs of respiratory melancholy and sedation (see WARNINGS and PRECAUTIONS).
Infants born to moms applying benzodiazepines late in pregnancy reported to practical experience signs of sedation and/or neonatal withdrawal
prescription drugs that demand prior authorization. This restriction calls for that precise medical requirements be achieved prior to the acceptance in the prescription.
miconazole vaginal will enhance the degree or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use warning/keep an eye on.
ribociclib will improve the degree or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use warning/keep track of.
verapamil will raise the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/watch.